A fishing community on a remote Maine island finds itself suddenly cut off from the rest of the world after the ferry stops coming. When people start to vanish, the terrified survivors realize that someone – or something – is hunting them.
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In an attempt to reconcile the problems in their relationship, Myra and James venture to an isolated cabin in the mountains. It is there they encounter an ancient evil that haunts the landscape, capable of turning people into deformed monsters. Not only will they be fighting for their relationship, they will be fighting for their lives.
In 19th century Baltimore, Isabel Porter, a girl stricken with grief from her parents’ untimely death, voluntarily checks herself into the Rosewood Institute. Subjected to bizarre and increasingly violent pseudo-scientific experiments in personality modification, brainwashing and mind control, she must escape the clutches of the Rosewood and exact her revenge, or else be forever lost.