Professional assassin Chev Chelios learns his rival has injected him with a poison that will kill him if his heart rate drops.
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The residents of a rural mining town discover that an unfortunate chemical spill has caused hundreds of little spiders to mutate overnight to the size of SUVs. It’s then up to mining engineer Chris McCormack and Sheriff Sam Parker to mobilize an eclectic group of townspeople, including the Sheriff’s young son, Mike, her daughter, Ashley, and paranoid radio announcer Harlan, into battle against the bloodthirsty eight-legged beasts.
The group will face a new zombie threat as a new breed of zombie has developed. This new super-zombie type is faster, bigger, and stronger than the previous strain of zombies and harder to kill. These super-zombies have started grouping up into a horde going from city to city leaving a path of destruction behind them.