Just three weeks before her wedding, Lola (Greta Gerwig) finds herself suddenly without a partner when her longtime fiance, Luke (Joel Kinnaman), dumps her. With her 30th birthday looming and being forced to re-enter the New York City dating scene, she feels adrift in a cold world. She leans on her friends (Zoe Lister-Jones, Hamish Linklater) for support but, after a series of romantic humiliations, professional blunders and boozy antics, Lola realizes that she alone is in charge of her fate.
When Sophie’s son, Garrett, develops a mysterious illness, she embarks on a search for answers. This leads her into the controversial world of Genetically Modified Organisms (GMOs) where a sociopolitical battle rages between organic farmers and big biotech corporations. As her desperation grows, so too does her quest for knowledge. And the deeper she goes, a more heightened sense of danger develops that preys on her state of mind, as she attempts to discover the root cause of her son’s illness.